Since this medicine is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time. This medicine may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you. Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients. Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Using loratadine and pseudoephedrine with other drugs that make you drowsy can worsen this effect.
Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Other drugs may affect loratadine and pseudoephedrine, including prescription and over-the-counter medicines, vitamins, and herbal products.
Tell your doctor about all your current medicines and any medicine you start or stop using. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
That said, researchers now seem to be arriving at better answers. Antihistamines are a class of medications that help relieve allergy symptoms. When you're exposed to an allergen, your body creates a chemical called histamine, which is part of a complex reaction by the immune system. Histamine is what causes typical allergy symptoms, such as sneezing, itching, and runny nose. Antihistimines block that reaction, thus alleviating allergy symptoms.
But your body also uses histamines to deal with physical damage and infection, such as with common cold. Colds can be caused by hundreds of different viruses, which don't cause the same symptoms in every person every time. While you may think of a cold as causing a cough or congestion, it's also possible that you may experience itchy eyes or a runny nose, which can mimic allergies.
Many types of antihistamines are available over the counter OTC. Several of the first-generation antihistamines cause drowsiness, but newer products are less likely to make you sleepy and have fewer side effects. Common antihistamines include:. What healthcare providers have learned over the years is that antihistamines seem to work for some people when they have colds, but not everyone.
Research has long been mixed as to the effectiveness, as well. It's possible that some symptoms—such as a runny nose—are caused by responses in the body that aren't related to histamine production, so antihistamines have no effect. It's also possible that some people just respond better to the medications than others.
Here's what contemporary research says about antihistamines as cold remedies:. Something studies do generally agree on, though, is that antihistamines are safe for adults. If you want to see how these drugs impact your cold symptoms, it's likely safe for you to do so, especially if you already take an antihistamine for allergies.
Keep in mind that it's always best to check with your healthcare provider before taking a new drug. Numerous studies say there's no evidence that antihistamines help relieve cold symptoms in children and point out that side effects are possible, so the risks outweigh any potential benefits. You have plenty of options for relieving your symptoms while waiting for a cold to run its course. Consider what's causing your discomfort, especially if choosing between over-the-counter cold medications , some of which may have several active ingredients ; it's best to use a product that treats only the symptoms you have.
You can also consider using non-medication options on their own or in addition to other remedies. For example:. Although research has been inconclusive, taking antihistamines for cold symptoms may be worth a try as long as your healthcare provider feels they are safe for you.
Just be aware that they may or may not help and could cause side effects. If you're already taking a multi-symptom cold medicine, make sure to read the ingredients list. We collected adverse effects information from the included trials.
We included 18 RCTs, which were reported in 17 publications one publication reports on two trials with participants of which were children suffering from the common cold, both naturally occurring and experimentally induced. The interventions consisted of an antihistamine as monotherapy compared with placebo.
However, there was no difference between antihistamines and placebo in the mid term three to four days to long term six to 10 days. When evaluating individual symptoms such as nasal congestion, rhinorrhoea and sneezing, there was some beneficial effect of the sedating antihistamines compared to placebo e.
Adverse events such as sedation were more commonly reported with sedating antihistamines although the differences were not statistically significant. Only two trials included children and the results were conflicting. The majority of the trials had a low risk of bias although some lacked sufficient trial quality information. Study characteristics The evidence is current to August Authors' conclusions:. To assess the effects of antihistamines on the common cold. Search strategy:. Selection criteria:.
Data collection and analysis:. Main results:.
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