Women should discuss with their healthcare providers the value of taking combined progesterone and estrogen replacement therapy or estrogen to prevent osteoporosis. There may be alternative treatments based on a woman's health profile. Health Home Conditions and Diseases. Hormone replacement therapy update To learn more about women's health, and specifically hormone replacement therapy, the National Heart, Lung, and Blood Institute of the National Institutes of Health NIH started a large study in The FDA states that hormone therapy should not be taken to prevent heart disease.
The National Heart, Lung, and Blood Institute offers the following suggestions for women who are deciding whether or not to use postmenopausal hormone therapy: The most important thing a woman can do in deciding to continue hormone replacement therapy is discuss the current research with her healthcare provider and health care team.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. This is not a complete list of side effects and others may occur.
Call your doctor for medical advice about side effects. Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Many drugs can interact with estradiol and progesterone. This includes prescription and over-the-counter medicines, vitamins, and herbal products.
Not all possible interactions are listed in this medication guide. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc.
Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Both males and females produce estradiol, and it is the most common type of estrogen in females during their reproductive years.
Too much estradiol may result in acne, loss of sex drive, osteoporosis, and depression. Very high levels can increase the risk of uterine and breast cancer. However, low levels can result in weight gain and cardiovascular disease. Levels of estriol rise during pregnancy , as it helps the uterus grow and prepares the body for delivery. Estriol levels peak just before birth. Ovaries: Estrogen helps stimulate the growth of the egg follicle.
Vagina: In the vagina, estrogen maintains the thickness of the vaginal wall and promotes lubrication. Uterus: Estrogen enhances and maintains the mucous membrane that lines the uterus. It also regulates the flow and thickness of uterine mucus secretions. Breasts: The body uses estrogen in the formation of breast tissue. This hormone also helps stop the flow of milk after weaning. Estrogen levels vary among individuals.
This fluctuation can sometimes produce effects such as mood changes before menstruation or hot flashes in menopause. Learn more about high estrogen levels and low estrogen levels here. An imbalance of estrogen leads to :. Some hereditary and other conditions can lead to high levels of estrogen in males, which can result in:. Estrogen therapy can help manage menopause symptoms as part of hormone therapy, which people usually refer to as hormone replacement therapy.
The treatment may consist solely of estrogen estrogen replacement therapy, or ERT , or it may involve a combination of estrogen and progestin, a synthetic form of progesterone. Hormone treatment is available as a pill, nasal spray, patch, skin gel, injection, vaginal cream, or ring. It may also help reduce the risk of osteoporosis, which increases when people enter menopause. Net to find guides on more than types of cancer and cancer-related syndromes, clinical trials information, coping resources, information on managing side effects, medical illustrations, cancer information in Spanish, podcasts, the latest cancer news, and much more.
For more information about ASCO's patient information resources, call toll-free The College of American Pathologists CAP , the leading organization of board-certified pathologists, serves patients, pathologists, and the public by fostering and advocating excellence in the practice of pathology and laboratory medicine worldwide. Key Points: Estrogen and progesterone receptors are found in breast cancer cells that depend on estrogen and related hormones to grow.
Background About estrogen and progesterone receptors Estrogen receptors ER and progesterone receptors PR; also called PgR may be found in breast cancer cells. Testing estrogen and progesterone receptors Testing the tumor for both estrogen and progesterone receptors is a standard part of a breast cancer diagnosis.
Questions to Ask Your Doctor To learn more about estrogen and progesterone receptor testing for breast cancer, consider asking your doctor the following questions: What are the results of the ER and PR tests on my tumor sample? What do they mean? Has a board-certified pathologist diagnosed my cancer? Can I obtain a copy of my pathology report laboratory test results?
Based on these test results, what treatments do you recommend and why? What are the possible side effects of these treatments? Helpful Links Read the entire clinical practice guideline published in the Journal of Clinical Oncology at www.
Net Guide to Breast Cancer About ASCO's Guidelines To help doctors give their patients the best possible care, ASCO asks its medical experts to develop evidence-based recommendations for specific areas of cancer care, called clinical practice guidelines.
Resources The best cancer care starts with the best cancer information.
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